00:00University of Michigan researchers have found a gut compound that may boost cancer immunotherapy.
00:05The compound is called DHB. It is made by gut bacteria when they break down dietary fiber.
00:11Researchers found DHB helps T-cells become memory cells. These cells can keep fighting tumors for
00:17longer. The team also created an oral drug form of DHB. This was designed to help the body absorb
00:23it better. Researchers tested it in mice with three cancers. These included melanoma,
00:29colorectal cancer, and breast cancer. Combined with checkpoint therapy, the treatment eradicated
00:34the tumors. The mice also developed immune memory. That helped protect them against the tumors
00:40returning. DHB also improved CAR T-cell therapy in the study. But there is an important limitation.
00:46The results have only been shown in mice so far. Human trials are needed to see if the treatment
00:51works in patients. Disclosure. This video contains stock footage and content created or enhanced
00:56using AI-assisted tools AI-generated.
