How does your immune system learn to recognize threats without attacking your own body?
Explore the human thymus in this premium 3D medical-science visualization.
Discover:
- Where the thymus is located in the chest.
- The difference between thymic cortex and medulla.
- How developing T-cells undergo positive selection.
- How cortical thymic epithelial cells test self-MHC recognition.
- How AIRE helps medullary epithelial cells present tissue-specific self-antigens.
- How negative selection removes many strongly self-reactive T-cells.
- How some developing cells become regulatory T-cells.
- How mature CD4 and CD8 T-cells leave the thymus.
The thymus is much more than an immune organ. It is a crucial training environment for developing a functional and self-tolerant T-cell population.
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